http://www.mesotheliomainfected.com A fact sheet about the risk factors, symptoms, diagnosis, and treatment of mesothelioma Tue, 19 Feb 2008 13:40:35 +0000 http://backend.userland.com/rss092 en .style1 { background-color: #CCCCFF; } Introduction to the SV40 Genome, SV40 Early Proteins Large Tumor (T)-Antigen and Small Tumor (t)-Antigen Simian virus (SV40) was discovered as one of the viruses capable of infecting Macacus rhesus as well as Macacus cynomolgus monkey kidney cells (1). It also had the possibility to infect and ... http://www.mesotheliomainfected.com/causes-and-prevention-of-technical-artifacts-when-studying-simian-virus-40-sv40-in-human-mesotheliomas.html .style1 { background-color: #CCCCFF; } Early in the 20th century endemic poliomyelitis gradually evolved into the most devastating epidemic in the Western world. Striking improve¬ments in public health, ironically, were accompanied by more frequent outbreaks of crippling poliomyelitis. By 1950, each new day brought more polio victims, an increasing sense of crisis, ... http://www.mesotheliomainfected.com/from-monkey-to-man-the-epidemiologic-evidence-of-an-association-between-simian-virus-40-and-malignancy.html .style1 { background-color: #CCCCFF; } Historical Background It was the Conference on the Biological Effects of Asbestos at the New York Academy of Sciences, organized by Irving Selikoff in November 1964 (1), that put both mesothelioma and asbestos on the map. Before that meeting, few people in the scientific or general community ... http://www.mesotheliomainfected.com/mesothelioma-and-asbestos-exposure.html .style1 { background-color: #CCCCFF; } The determination of whether an abnormal asbestos exposure took place is important in mesothelioma cases because of the potential for financial compensation and for the assessment of the likelihood of further cases occurring from similar occupational, paraoccupational, or environmental circumstances. One should be aware that not all ... http://www.mesotheliomainfected.com/determination-of-asbestos-exposure-by-pathology-and-clinical-history.html .style1 { background-color: #CCCCFF; } Cancer has been known for millennia, but the understanding we have of its origins and causes are comparatively recent. Ancient Egyptians first recorded cancer as a disease some 4500 years ago. However, it wasn’t until the 18th century that observations on environmental cancers were made, ... http://www.mesotheliomainfected.com/malignant-mesothelioma-and-erionite.html .style1 { background-color: #CCCCFF; } Over the past 50 years epidemiology has been involved in the field of cancer research. By studying the association between risk factors and cancer occurrence, epidemiologists have contributed to the identifica¬tion of the most important determinants of cancer in humans. In recent years, epidemiologists have concentrated on ... http://www.mesotheliomainfected.com/molecular-epidemiology-of-mesothelioma-2.html .style1 { background-color: #CCCCFF; } Fibers and fibrous minerals, for example, the asbestos minerals, erion-ite (one of the many natural and synthetic zeolite species) (1), fiber¬glass, or other silica forms (diatoms) have been shown to be extremely hazardous. Their airborne character is paramount, and the specific gravity of the species, the size, ... http://www.mesotheliomainfected.com/molecular-epidemiology-of-mesothelioma.html .style1 { background-color: #CCCCFF; } Advances in molecular biology over the past decade have improved our understanding of genetic, transcriptional, and translational alter¬ations in human cancers. The sequencing of the human genome has resulted in the identification of many known and novel genes. Several groups are engaged in determining the interactions and ... http://www.mesotheliomainfected.com/genomics-and-proteomics-in-mesothelioma.html .style1 { background-color: #CCCCFF; } Malignant mesotheliomas are highly aggressive diffuse tumors aris¬ing from mesothelial-lined surfaces. Mesotheliomas spread along mesothelial-lined surfaces to involve the pericardium, contralateral hemithorax, and peritoneal cavity by invasion through the diaphragm. The resulting tumor often forms diffuse thickening of involved surfaces rather than solitary rounded lesions as seen in ... http://www.mesotheliomainfected.com/extracellular-matrix-and-mesothelioma-some-clues-to-the-invasive-behavior-of-mesothelioma.html .style1 { background-color: #CCCCFF; } Although there is a considerable body of published literature concern¬ing the putative role of immune status in the pathogenesis and pro¬gression of common malignancies such as lung and breast cancers, this area of research previously had been relatively neglected with respect to malignant mesothelioma, a comparatively uncommon ... http://www.mesotheliomainfected.com/immune-status-and-mesothelioma.html